Extraerythrocytic malria and chloroquine

Discussion in 'Plaquenil' started by Mobi, 03-Mar-2020.

  1. Tatty User

    Extraerythrocytic malria and chloroquine

    Some parasites differentiate into sexual erythrocytic stages (gametocytes) . Blood stage parasites are responsible for the clinical manifestations of the disease.

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    Chloroquine might be getting new life as an antiviral treatment for the novel coronavirus that emerged in Wuhan, China in late 2019 and has infected some 25,000 people in more than 25 countries. For decades, the drug was a front-line treatment and prophylactic for malaria. Education and information regarding choosing a drug to prevent malaria, including a list of all available drugs and reasons for taking or not taking a certain drug. Paris AFP A treatment for malaria, chloroquine, has shown signs of effectiveness against the new coronavirus, according to a preliminary study carried out in China, but several experts call for caution in the absence of further studies and because of its side effects which can be serious.

    The parasites’ multiplication in the mosquito is known as the sporogonic cycle . The gametocytes, male (microgametocytes) and female (macrogametocytes), are ingested by an mosquito during a blood meal .

    Extraerythrocytic malria and chloroquine

    Chloroquine - Wikipedia, CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria

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  5. Plasmodium parasites are agents of rodent's malaria. The life cycle is similar to another malaria parasite of mammals. The study on the rodent's malaria can be a good model of human malaria infection. Quinine is an antimalarial drug which is made from Cinchona bark. The mode of action of quinine is similar to chloroquine.

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    The clinical usefulness of chloroquine, and in some recent cases of quinine as well, has been much reduced by the evolution and spread of chloroquine resistant malaria parasites. The mechanism of resistance involves a reduced accumulation of the drug, although again the mechanism involved is controversial. Chloroquine, a widely used anti-malaria and autoimmune disease drug, has been known to block virus infections by changing the acidity and basicity value inside the cell and interfering receptors. Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

  6. tbo XenForo Moderator

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. DMARDs for Treating Rheumatoid Arthritis Hydroxychloroquine MedlinePlus Drug Information Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus
  7. Wolter Moderator

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  8. Tigrenok Moderator

    Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset.

    Plaquenil Uses, Dosage & Side Effects -