Plaquenil and dermatomyositis

Discussion in 'Plaquenil Generic' started by macik, 13-Mar-2020.

  1. Adamovitch Guest

    Plaquenil and dermatomyositis


    Note the presence of a confluent, erythematous eruption that is not only in a photodistribution but is now on the breasts and upper abdomen. RIC ANTHONY KOLER, MAJ, MC, USA, Fox Army Health Center, Redstone Arsenal, Alabama ANDREW MONTEMARANO, MAJ, MC, USA, Walter Reed Army Medical Center, Washington, D. An association with other connective tissue disorders (overlap syndrome) and malignancy make this diagnosis particularly important to primary care physicians.

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    Juvenile dermatomyositis JDM is an inflammatory disease of the muscle myositis, skin, and blood vessels. Patients with JDM have varying symptoms ranging from mild muscle weakness like difficulty getting out of a chair or difficulty turning over in bed to severe symptoms including profound weakness or difficulty swallowing. In dermatomyositis, an abnormal immune reaction appears to lead to obstructive inflammatory changes of blood vessels within muscle, connective tissues of the skin, and other tissues; patchy degeneration, wasting atrophy, and regeneration of muscle fibers; thinning of the outermost skin layer epidermis; and/or other associated findings. Hydroxychloroquine also known by its popular brand name Plaquenil is an oral medication that is commonly used to treat a variety of autoimmune diseases including systemic lupus, dermatomyositis, rheumatoid arthritis, Sjogren’s and many other conditions as well. In the field of hair loss, conditions such as lichen planopilaris, frontal fibrosing alopecia and discoid lupus are frequently treated with hydroxychloroquine.

    Dermatomyositis is an idiopathic inflammatory myopathy with characteristic skin manifestations. Although the disorder is rare, with a prevalence of one to 10 cases per million in adults and one to 3.2 cases per million in children, early recognition and treatment are important ways to decrease the morbidity of systemic complications.

    Plaquenil and dermatomyositis

    Dermatomyositis An Acute Flare and Current Treatments, Dermatomyositis - NORD National Organization for Rare Disorders

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  6. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis. Objective To determine if adverse cutaneous eruptions due to hydroxychloroquine are more common in patients with dermatomyositis than in those with cutaneous lupus erythematosus.

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    If this is true, then you have dermatomyositis DM, not PM. The diagnosis of DM in the skin is made by a combination of clinical and pathological findings. If DM, then you might benefit from a change in treatment to include plaquenil with or without methotrexate or mycophenolate. Dec 12, 2019 Hydroxychloroquine also known by its popular brand name Plaquenil is an oral medication that is commonly used to treat a variety of autoimmune diseases including systemic lupus, dermatomyositis, rheumatoid arthritis, Sjogren’s and many other conditions as well. In the field of hair loss, conditions such as lichen planopilaris, frontal fibrosing alopecia and discoid lupus are frequently treated with hydroxychloroquine. The mechanism of action is thought to be anti-inflammatory, but Plaquenil also seems to reduce sensitivity to sunlight. It has also been noted recently that smoking reduces the effectiveness of Plaquenil in treating lupus, thus, smoking cessation should be instituted in all patients taking Plaquenil. More About Autoimmune diseases DERMATOMYOSITIS

     
  7. Alexitis Guest

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Fibro,RA, and Sjogrens - Plaquenil for CFS. ProHealth Fibromyalgia, ME/CFS and. My current treatment protocol for chronic Lyme and.
     
  8. anlimit New Member

    Final Diagnosis -- Hydroxychloroquine myopathy - UPMC DIAGNOSIS. Hydroxychloroquine myopathy. DISCUSSION. Hydroxychloroquine HCQ, a commonly used drug for various autoimmune conditions, is widely distributed into cardiac and skeletal muscle tissue. It is a large amphiphilic molecule that can cause both myofiber necrosis and vacuolar myopathy.

    Hydroxychloroquine, the drug that could stop COVID-19 - archyde