Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. How does plaquenil work for sjogren& 39 Hydroxychloroquine usmle mechanism of action A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. If you will be taking chloroquine long-term, your healthcare provider will monitor you with periodic blood tests. This medication may cause hearing problems, including ringing in the ears, reduced hearing, and loss of hearing. Substitutes and alternatives to chloroquine for uses like Malaria, Extraintestinal amebiasis and Lupus chloroquine Alternatives & Similar Drugs - Skip to full site navigation The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Indication of chloroquine Chloroquine - FDA prescribing information, side effects., Precautions and Warnings With Chloroquine Buy chloroquine online ukHydroxychloroquine lupus pregnancyHydroxychloroquine bleedingPlaquenil vertigo Chloroquine undergoes appreciable degradation in the body. The main metabolite is desethylchloroquine, which accounts for one fourth of the total material appearing in the urine; bisdesethylchloroquine, a carboxylic acid derivative, and other metabolic products as yet uncharacterized are found in small amounts. CHLOROQUINE PHOSPHATE, USP. Chloroquine Alternatives & Similar Drugs -. Chloroquine is a potent inhibitor of SARS coronavirus.. Chloroquine is an antimalarial and amoebicidal drug. The drug possesses antimalarial actions and exerts a beneficial effect in lupus erythematosus chronic discoid or systemic and acute or chronic rheumatoid arthritis. The precise mechanism of action is not known. Indication • Malaria Vivax malaria • Amoebic liver abscess Mar 16, 2020 “There is rational, pre-clinical evidence of effectiveness and evidence of safety from long-term clinical use for other indications to justify clinical research on chloroquine in patients with. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite.