Hydroxychloroquine in lupus pregnancy

Discussion in 'Hydroxychloroquine Sulfate' started by grooviev, 08-Mar-2020.

  1. Nick80 Moderator

    Hydroxychloroquine in lupus pregnancy


    Less than 50% of pregnancies in women with lupus have complications, but all lupus pregnancies are considered high-risk. Lupus can complicate pregnancy with an increased risk of miscarriage, premature delivery, and preeclampsia, as well as heart problems in the baby.

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    Clowse et al. found that women who stopped taking HCQ had increased lupus activity and increased lupus flares during pregnancy. High activity lupus was defined as a physician's estimate of activity PEA greater than 2 occurred in twice as many pregnancies in which HCQ treatment was stopped as in those in which HCQ was continued. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus. Hydroxychloroquine is sold under several brand names, including Plaquenil®. For more information on rheumatoid arthritis or lupus in pregnancy please see. Hydroxychloroquine Plaquenil is recommended for all women with lupus during pregnancy. Hydroxychloroquine was originally an antimalarial medication that was found to reduce the risk of lupus flares during pregnancy as well. It isn't known to cause any problems in babies and may help prevent neonatal lupus.

    “Preconception counseling allows women who have lupus to discuss their personal health with their doctor to assess risks based on how lupus has affected her thus far,” says Larry Matsumoto, MD, maternal fetal specialist at Atlanta Perinatal Consultants. If you have lupus and are considering having a baby, consider these tips to ensure a safe pregnancy and healthy baby.

    Hydroxychloroquine in lupus pregnancy

    Hydroxychloroquine in Lupus Pregnancy A Meta-Analysis of., Hydroxychloroquine MotherToBaby

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  5. Summary. SLE is a multi-organ autoimmune disease that affects women of childbearing age. Renal involvement in the form of either active lupus nephritis LN at the time of conception, or a LN new onset or flare during pregnancy increases the risks of preterm delivery, pre-eclampsia, maternal mortality, fetal/neonatal demise, and intrauterine growth restriction.

    • Obstetric Nephrology Lupus and Lupus Nephritis in Pregnancy.
    • Medication for lupus during pregnancy BabyCenter.
    • Lupus and Pregnancy Tips for Living with Lupus While Pregnant.

    Abstract. OBJECTIVE To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine HCQ. METHODS The case records of women n = 33 exposed to HCQ during their pregnancies n = 36 and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus activity, obstetric experience, and infant outcome. Plaquenil hydroxychloroquine has a good safety record in lupus pregnancy, and is usually continued if needed to control maternal lupus. Management and Monitoring. Lupus pregnancy should be timed to coincide with a period of good disease control if at all possible. We conducted a randomized, controlled study to assess the need for hydroxychloroquine HCQ during lupus pregnancy and to assess safety. Twenty consecutive pregnant patients with similar characteristics were enrolled. The HCQ group included eight patients with systemic lupus erythematosus SLE and two with discoid lupus erythematosus DLE.

     
  6. dmsoh Moderator

    The study is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Rashes (redness) has been reported by people with rheumatoid arthritis, high blood pressure, multiple sclerosis, hepatitis c, high blood cholesterol. Hydroxychloroquine Reviews Everyday Health Plaqunil rash - Hydroxychloroquine Oral Route Side Effects - Mayo Clinic
     
  7. AlexInoz XenForo Moderator

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  8. starosta Well-Known Member

    PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION Hydroxychloroquine sulfate sulfate base, and are for oral PLAQUENIL® HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION PLAQUENIL h. ydroxychloroquine sulfate is a. white or practically white, crystalline. powder freely. soluble in water; practically insoluble in alcohol, chloroform, and in ether. The. chemical. name for

    Hydroxychloroquine inhibits autophagy. - PubMed Central PMC