Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Dark palate hydroxychloroquine How does chloroquine kill the malaria parasite Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine may also be used for purposes not listed in this medication. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Long term use of hydroxychloroquine Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, RA and Hydroxychloroquine How Effective is it for Rheumatoid. A patient will begin taking hydroxychloroquine for rheumatoid arthritisiHydroxychloroquine pharmacokineticsHydroxychloroquine plaquenil coupons Hydroxychloroquine HCQ was suggested to play a role in lowering antiphospholipid antibody titers and preventing thrombotic recurrences in patients with systemic lupus erythematosus, but few data are available in patients with primary antiphospholipid syndrome PAPS. Long-term use of hydroxychloroquine reduces antiphospholipid.. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Hydroxychloroquine Side-effects, uses, time to work. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine HCQ and chloroquine CQ are commonly used medications for rheumatoid arthritis RA, systemic lupus erythematosus SLE, and other connective tissue disorders. More than 1.5 million persons have these conditions, and many of them receive HCQ as the initial treatment. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes.