If you’ve had it for some time, you may even be experiencing the joint deformities that can occur as RA progresses. As you know, any joint deformity can take a significant toll on your joint function as well as your overall quality of life. Fatal dose of chloroquine Hydroxychloroquine and herb combination Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications Results of a two‐year, randomized, double‐blind, placebo‐controlled trial Plaquenil hydroxychloroquine and Rheumatrex and Trexall methotrexate are used to treat rheumatoid arthritis. Plaquenil is also used to treat or prevent malaria, and to treat symptoms of discoid or systemic lupus erythematosus. Rheumatrex and Trexall are also used to treat some cancers and severe skin diseases such as severe psoriasis. The distinction between using methotrexate to treat cancer and to treat rheumatoid arthritis is important. Technically speaking, methotrexate is a “cancer drug” — and it’s used to treat different kinds of cancer, including breast cancer. That’s because methotrexate attacks fast-dividing cells, which include cancer cells. Leisurely pursuits like gardening or taking long walks may have lost their appeal as well, largely as a result of the pain and inflammation these joint-based movements can trigger. RA usually attacks the joints of the hands and feet first, which means even simple activities like tying a shoe, brushing your teeth, combing your hair, or getting dressed in the morning can become painful enterprises. Plaquenil and methotrexate for rheumatoid arthritis Plaquenil and pain" Rheumatoid Arthritis Community., Plaquenil vs. Rheumatrex, Trexall Prescription Treatment for. Plaquenil for diarrheaAreas of chloroquine resistant malaria Original Article from The New England Journal of Medicine — Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications Treatment of Rheumatoid Arthritis with Methotrexate Alone.. Common Questions About Taking Methotrexate for Rheumatoid.. Methotrexate or Plaquenil? DailyStrength. One of the most popular and also most effective of these is a folate analog called methotrexate MTX. It’s a treatment option with one of the longest and most well-established safety profiles of any rheumatoid arthritis drug on the market. Methotrexate and RA Treatment Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Dec 19, 2017 It’s important to remember that those of us living with rheumatoid arthritis who use immunosuppressant medications, such as one of the biologics or methotrexate, should avoid receiving live virus vaccines for risk of developing the infection. This is why the shingles vaccine has been off limits.