Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Malaria medicine hydroxychloroquine Plaquenil ask doctor Basically, plaquenil's effect is to modulate the immune system, which is something that could be quite beneficial for some of us. You can do what you want, but you might want to consider giving plaquenil more of a chance, and be far more wary of the prednisolone prednisone/steroid. Take 2 x Paracetamol in evening, enhances tamsulosin performance and stops us getting up for a pee so often during the night. Do not drink 2 lites of Green tea and coffeee every day as I had been doing, I litre is enough, and best not to drink too much before bedtime. All fairly simple and straightforward, can't think why I had a problem with it? I am concerned, however, that I will be running to the bathroom during the night. Has anyone had the same problem with plaquenil that I have, switched to taking the dose at night but not had problems with getting diarrhea attacks at night? Do you take it with supper or just before bedtime? Thanks. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Why is plaquenil taken at bedtime Hydroxychloroquine Indications, Side Effects, Warnings., When to take Tamsulosin? For best results? - Localised cancer. Chloroquine retinopathy faPlaquenil sarcoidosis hypercalcemia The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Taking Plaquenil for Rheumatoid Arthritis. New to Plaquenil - question for you. Hydroxychloroquin and acid reducers - Sclero Forums MAIN.. Severe Interactions These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in formation. These medications may interact and cause very harmful effects. Consult your healthcare professional e.g. doctor or pharmacist for more in formation. I asked the rheumy whether I could take both doses of Plaquenil together but he said it was better to space them out. I find they make my reflux worse if I take a dose too close to bedtime and if my reflux is bad I need to take a second dose of Lanzoprazole before bed anyway. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used.