I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Cirrus oct plaquenil Plaquenil usage and autism When my doc was telling me about. the plaquenil and some symptoms I might experience, he told me to stop taking it if I felt weird in any way. ok, my tongue swelled and felt itchy and burny. Well, after day three I decided it wasn't a minor thing and called my doc. So now, no more plaquenil. I am on nothing and I'm in pain all over again. yay me. That's a strong plus for Plaquenil since many other drugs that work on the immune system also weaken it and can thereby increase the risk for infection substantially. Plaquenil is a slow acting drug. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Stopped plaquenil now symptoms have returned Rheum had me stop plaquenil on it for +Ana, symptoms to., Plaquenil Hydroxychloroquine for use in Autoimmune. How long for chloroquine to workLichen planopilaris plaquenilHydroxychloroquine lab monitoring atiPlaquenil guidelines aoaWhitepill with plaquenil Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Taking Plaquenil for Rheumatoid Arthritis. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Rheum had me stop plaquenil on it for +Ana, symptoms to see.. Sep 17, 2014 Hi Nina, I haven't stopped taking plaquenil personally so I can't comment from my experience but I'm sure I have read of others who have. As I recall I have read that several people who have stopped taking it have seen a rebound/return of their symptoms which had previously become dormant while taking it. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Severe depression and anxiety, overall itching, pain and stiffness increased instead of decreased. First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring.