Please review the following URL and make sure that it is spelled correctly. Liver function test abnormal is found among people who take Plaquenil, especially for people who are female, 60 old , have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Osteoporosis. Metabolism of chloroquine Chloroquine dormant Hydroxychloroquine is an antimalarial drug used to prevent and treat malaria. Hydroxychloroquine Plaquenil is also a disease-modifying anti-rheumatic drug DMARD used to treat both acute and chronic rheumatoid arthritis, systemic lupus erythematosus, and discoid lupus erythematosus. Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal BMPR-II degradation. Circ Res. 2013 ; 112 1159–1170. Jan 22, 2016 I also am on plaquenil and have been for several years. Diagnosed with systemic scleroderma in 2002. I have developed pulmonary fibrosis in the lower lobe of my left lung last year and have PFT's done every 6months. On e Health Me, you can evaluate side effects and drug interactions from millions of FDA reports. This study is created by e Health Me based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration (FDA), and is updated regularly. Plaquenil pulmonary hypertension DailyMed - PLAQUENIL- hydroxychloroquine sulfate tablet, Chloroquine in Pulmonary Arterial Hypertension. Plaquenil and cellceptChloroquine as antiamoebicCan you take plaquenil while pregnantWhat happens when you drink red wine on hydroxychloroquineHydroxychloroquine lupus dosage Patients may present with atrioventricular block, pulmonary hypertension, sick sinus syndrome or with cardiac complications. ECG findings may include atrioventricular, right or left bundle branch block. Signs or symptoms of cardiac compromise have appeared during acute and chronic treatment. Plaquenil - FDA prescribing information, side effects and uses. Just Diagnosed with Crest Syndrome & Prescribed Plaquenil.. Plaquenil hydroxychloroquine – New Warnings. Pulmonary arterial hypertension PAH associated with connective tissue disease PAH-CTD is the second most common cause of pulmonary hypertension PH ie, group 1 of the European Society of Cardiology/European Respiratory Society pulmonary hypertension classification after idiopathic/heritable PAH. 1 x 1 Humbert, M. Sitbon, O. Chaouat, A. et al. Pulmonary arterial hypertension in France. Pulmonary Hypertension diagnosed Oct '07. I don't know if Plaquenil is the answer, but I know that if it's something that is disease modifying, and can help with. Pulmonary hypertension PH is a disease that causes high blood pressure in the lungs due to narrowing in the pulmonary arteries. It is a rare but life-threatening condition that develops when narrowed vessels, which are responsible for transporting the blood from the heart to the lungs, force the heart to work harder to pump blood.