I'm currently on plaquenil 400mg daily and methotrexate 25mg weekly`many thanks in advance Did you tell the prescriber that you were on MTX? MTX should not be taken with any penicillin type drug. Hydroxychloroquine sulfate drug interactions Hydroxychloroquin eye In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. This could increase your risk for side effects or decrease the effectiveness of the medicines. To help prevent potentially negative Plaquenil drug interactions, tell your healthcare provider about all other medications you are taking before starting Plaquenil. Plaquenil Interactions - Antibiotics Home PageMedicines that may cause Plaquenil interactions with Plaquenil, interactions can occur that medications you are taking before starting Plaquenil. Hydroxychloroquine tablets - Plaquenil, Quinoric PatientIt can take several months before you feel the full benefit of the treatment. I'm honestly just curious because I've taken penicillin abx many times while on methotrexate... You also need to be very careful taking MTX with any type of chest infection and should not take it at all if you have pneumonia. I just finished pharmacology in nursing school, and also take methotrexate, and I've never heard that it shouldn't be taken with penicillin antibiotics - do you have any resources? Can you take antibiotics with plaquenil Antibiotics and meds -, Plaquenil Interactions - Antibiotics Home Page Plaquenil lyme cystsHydroxy chloroquine 200 mgMoa chloroquine Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. You can cut or crush this oral tablet. Take each. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Can You Take Benadryl With Plaquenil - Choice TV. Is Plaquenil an Antibiotic?. Never, it's the Plaquenil that's helped me a great deal I love the stuff. but I do take Advil in addition. So if you're not getting enough pain relief from Plaquenil alone, you could ask your dr. whether you can add an OTC like Advil. I don't think Plaquenil is an antibiotic. I think it's an antimalarial & is classified as a DMARD =. Please ask your doctor to be sure, but I've used probiotics while I was taking prednisone, plaquenil, methotrexate, Arava/leflunomide, gabapentin, keppra another seizure med, bystolic a beta blocker, tramadol, verapamil, diltiazem, diclofenac, and several antibiotics. Never had any interaction that I was aware of. You can take Advil or another NSAID while taking Plaquenil hydroxychloroquine as long as NSAID isn't contraindicated for you. Asked in Health, Medication and Drugs, Antibiotics, Xanax.