Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine contre indication Plaquenil mouth side effects Plaquenil and eye problems I think it's due to Hydroxycholoroquine-induced hyperpigmentation an example of drug-induced skin pigmentation. I thought it worth showing those of you on the medication. Why is it so much worse on the right forearm? Well she's only just started to drive again. Patients who get a drug exanthem with hydroxychloroquine may be able to tolerate chloroquine, while an urticarial reaction from hydroxychloroquine would preclude use of chloroquine. Other side effects include nausea, headaches, myopathy, and bluish-gray hyperpigmentation of the skin. The incidence of hydroxychloroquine-related hyperpigmentation in patients with systemic lupus erythematosus is about 7%, but unlike hydroxychloroquine-related retinopathy, there is no clear association with cumulative dose or duration of use.1 Roughly half of cases occur in the first five years of treatment. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil hyperpigmentation Plaquenil Side Effects Common, Severe, Long Term -, Subacute Cutaneous Lupus Erythematosus SCLE - Dermatology. What is the drug hydroxychloroquine used forDoes hydroxychloroquine cause cirrhosisPlaquenil and nephritisPlaquenil aao A total of 41 patients 38 women and 3 men were included in the study. The mean age was 39.2 ± 15.4 years. The hydroxychloroquine was indicated for systemic lupus erythematosus in 73.2%, dermatomyositis in 12.2%, rheumatoid arthritis in 9.8%, actinic lichen and sarcoidosis each in 2.4%. Hydroxychloroquine-induced hyperpigmentation in systemic.. Hydroxychloroquine-related skin discoloration CMAJ. ICD-10-CM Diagnosis Code T37.8X5A Adverse effect of.. Drug-induced pigmentation is not generally associated with any systemic toxicity and thus has an excellent prognosis. With some exceptions, pigmentation is usually reversible and slowly fades with discontinuation of the drug. Drug-induced skin pigmentation accounts for 10–20% of all cases of acquired hyperpigmentation. Pigmentation may be induced by a wide variety of drugs; the main ones implicated include non-steroidal anti-inflammatory drugs NSAIDs, phenytoin, antimalarials, amiodarone, antipsychotic drugs, cytotoxic drugs, tetracyclines, and heavy metals. Druginformer Identified Side Effects Arthralgia, Chest pain, Pruritus, Skin hyperpigmentation, Oral disorder, Lupus-like syndrome. Posted By Anonymous in on July 11, 2006 @ am “. Plaquenil worked well on my symptoms, but it started to make me itchy and caused skin pigmentation.