Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil pregnancy category australia Hydroxychloroquine mechanism of action usmle Plaquenil heat I am having severe RA again in my feet and ankles. Happens about at the end of every month now. Even since I've started the meds. I am on Plaquenil right now, but I am wondering how well it works since my pain has come back. I have heard some people switch over to Methotrxate if the Plaquenil doesn't work. 4 replies Apr 10, 2019 To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. Hello kelpie21, It can be a hard road, can't it? Hydroxychloroquine does take a while to take effect. Arthritis UK gives a figure of around 12 weeks, whilst the American College of Rheumatology says, "symptoms can start to improve after 1-2 months, but it may take up to 6 months before the full benefits are felt". Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. How long before plaquenil works Plaquenil.long do I have to wait? DailyStrength, Plaquenil Uses, Dosage & Side Effects - What are symptoms of plaquenil eye problemsOcular follow-up in regards to hydroxychloroquineHydroxychloroquine interaction with cyclobenzaprineIs prednisone and plaquenil safe during pregnancy I had a skin rash from plaquenil hydroxychloroquine. I was put on a 21 day taper of prednisone. How long befor more I had a skin rash from plaquenil hydroxychloroquine. I was put on a 21 day taper of prednisone. How long before the prednisone increases my odds of catching viruses? How long does it take for plaquenil hydroxychloroquine to.. How long until Hydroxychloroquine takes effect - LUPUS UK. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil takes quite a long time to get to its peak effectiveness depending on what you read, anywhere from 3 months to a year. Unless you are having significant side effects, try to give it at least 6 months before you decide it doesn't work for you. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. I searched the board for info on this drug, but couldn't find a thread that answered my question. How long was it until you started to see some benefit from pilocarpine? I am starting at a low dose of 5mg x 3 daily. The handout says it could take 12 weeks before it starts to work, and I have only been on it 3 days. I want it to work NOW.