Amiodarone, an antiarrhythmic, is the most common cause of corneal verticillata, followed by chloroquine, hydroxychloroquine, indomethacin, and phenothiazines. A comprehensive list of systemic drugs associated with corneal verticillata is given in . Plaquenil standard of care Plaquenil toxicity Because of the risk of ECG changes and hypotension, use caution during aerobic exercise and other forms of therapeutic exercise. Assess exercise tolerance frequently blood pressure, heart rate, fatigue levels, and terminate exercise immediately if any untoward responses occur See Appendix L. Implement appropriate manual therapy techniques, physical agents, therapeutic exercises, and. Name /bks_53161_deglins_md_disk/hydroxychloroquine 03/07/2014 AM Plate # 0-Composite pg 1 # 1 PDF Page #1 Canadian drug name. Genetic Implication. Chloroquine and hydroxychloroquine can pass through the placenta, but do not appear to cause harm to the baby and likely is beneficial to both mother and baby by an improved pregnancy outcome. Both drugs are excreted in breast milk. Studies of pregnant mice revealed that the drug accumulates in the fetal retina. The deposits typically resolve with discontinuation of the responsible agents. It is unusual for these deposits to result in reduction of visual acuity or ocular symptoms, although this has occurred in some patients. Hydroxychloroquine keratopathy Drug-induced corneal epithelial changes - ScienceDirect, Avoiduse Pedi Long-termuse hydroxychloroquine hye-drox. Long term chloroquine prophylaxisPlaquenil and the sunPlaquenil and celiacStop hair loss plaquenilMethylene blue falciparum target chloroquine These deposits occur in various levels of the cornea. Corneal verticillata, also called vortex keratopathy, are one type of corneal deposits. Verticillata are readily recognizable by their distinct appearance as fine, golden-brown or gray opacities that are almost always bilateral. Corneal verticillata - Amiodarone. Chloroquine And Hydroxychloroquine Toxicity - Abstract.. Chloroquine And Hydroxychloroquine Toxicity - StatPearls.. Start studying Hydroxychloroquine Plaquenil. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Hydroxychloroquine is generally a safe treatment with occasional mild nausea, cramps and mild diarrhea. To prevent reversible keratopathy, corneal exams twice yearly are recommended. Maculopathy is rare but should be screened for with biannual retinal examinations. REFERENCES. 1. Hydroxychloroquine sulfate and Abstral drug interaction Keratopathy -a study from FDA data Summary There is no Keratopathy reported by people who take Hydroxychloroquine sulfate and Abstral yet.